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In this instance, abrupt discontinuation of the opioid may bring about a withdrawal syndrome. In the event the discontinuation of opioids is therapeutically indicated, gradual tapering on the drug more than a two-week period will avert withdrawal signs or symptoms. The severity of the withdrawal syndrome is dependent totally on the daily dosage of

Physical dependence occurs when Your entire body develops a tolerance towards the drug, necessitating far more of it to obtain a certain result.Tend not to use with some other drug containing acetaminophen with no asking your doctor or pharmacist first. Acetaminophen is in lots of nonprescription and prescription prescription drugs (for instance di